Hypothalamic–pituitary–adrenal axis, neuroendocrine factors and stress

Trans-generational effects of prenatal stress on the neuroendocrine stress axis in rats.

Axis-by-Axis Stress Minimization

Graph drawing algorithms based on minimizing the so-called stress energy strive to place nodes in accordance with target distances. They were first introduced to the graph drawing field by Kamada and Kawai [11], and they had previously been used to visualize general kinds of data by multidimensional scaling. In this paper we suggest a novel algorithm for the minimization of the Stress energy. U...

Response of the nitrergic system to activation of the neuroendocrine stress axis

Exposure to stressful stimuli causes activation of the hypothalamic-pituitary-adrenal axis which rapidly releases high concentrations of glucocorticoid stress hormones, resulting in increased cellular metabolism and spontaneous oxygen and nitrogen radical formation. High concentrations of nitrogen radicals, including nitric oxide, cause damage to cellular proteins in addition to inhibiting comp...

The Stress Axis Gone Awry: A Possible Neuroendocrine Explanation for Increased Risk of Completed Suicide

• While not useful as a screening tool or specific diagnostic indicator, a patient’s DST status provides useful information about the character of the depressive state, particularly as it relates to agitation and anxiety. The HPA Axis and Mental Status The HPA axis is crucial to survival. At baseline, it maintains homeostasis and circadian rhythms through a finetuned feedback loop, consisting o...

The role of the hypothalamic-pituitary-adrenal axis in neuroendocrine responses to stress

Animals respond to stress by activating a wide array of behavioral and physiological responses that are collectively referred to as the stress response. Corticotropin-releasing factor (CRF) plays a central role in the stress response by regulating the hypothalamic-pituitary-adrenal (HPA) axis. In response to stress, CRF initiates a cascade of events that culminate in the release of glucocortico...